Men who exercise regularly and strenuously in their early years are less likely to develop parkinson's disease when they are older, a new study suggests.
The health histories of 48,000 men indicated that those who had been the most active had half the risk of Parkinson's disease as those who had been the least active, the lead author of the work, Dr. Honglei Chen of the Harvard School of Public Health reported in the journal Neurology. While the association between exercise and the occurrence of Parkinson's appeared strong, the explanation is uncertain.
"This study suggests either that higher levels of physical activity may lower the risk of Parkinson disease," the researchers wrote, or that men who are predisposed to it "tend to avoid strenuous physical activity in their early adult years."
The researchers drew on information gathered in the Health Professionals Follow-Up Study, which has been following the health of thousands of men since 1986, and the Nurses' Health Study, which began in 1976.
While women who exercised as young adults also experienced fewer cases of Parkinson's, the data were not strong enough to establish a link, the researchers said.
The volunteers in the study were asked to provide detailed information about their habits, including their participation in activities like hiking and swimming.
Both men and women reduced their levels of physical activity several years before they learned they had Parkinson's disease, reflecting what the authors called "the insidious nature of the disease and unrecognized physiopathologic changes that may limit the patients' capability to tolerate vigorous exercises."
In New York Times.
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