Antipodean Pharmaceuticals Initiates Phase 2 Trial In Parkinson's Disease

28 May 2006 - Antipodean Pharmaceuticals, Inc. today announced it has initiated Phase 2 clinical trials to test the efficacy of its lead compound MitoQ (mitoquinone) in patients with Parkinson's Disease in New Zealand and Australia. (...)

Antipodean's compound, MitoQ, is based on a novel technology, targeted lipophilic cations, that transport and concentrate antioxidants into the mitochondria where they accumulate up to 1000 fold. There they have been shown to significantly interrupt oxidative damage, which is implicated as a catalyst in Parkinson's and other neurological diseases. MitoQ was invented by Professor Robin Smith at the University of Otago in New Zealand and Dr Michael Murphy a former colleague at Otago who is now in the UK. (segue...) Fonte: Antipodean Pharmaceuticals, Inc.